Welcome, Furong! CBS17: Duke researchers say new method to prevent/treat COVID shows promise in animal studies, WGHP FOX-8: Scientists study a mutation-proof treatment for COVID-19, WTVD ABC-11(45-second video):New treatment in development at Duke shows promise against COVID-19, The News & Observer: Duke researchers edit genes to prevent, treat COVID-19 in the lab. Contact the Duke WordPress team. Ben Sunkel from the Ohio State Biochemistry Graduate Program (OSBP) joined the Wang lab as a graduate student. In October 2009, he was sentenced to 11 years for taking more than RMB 1 million (over 100,00) in bribes. Starring Chang Chen, Cecilia Liu and Wang Qianyuan, the film was released in China on August 7, 2014. She graduated from the University of Peking in 1903 and then worked as a teacher before becoming a politician. Please read the Duke Wordpress Policies. We defend the internet and other systems of communication against illegitimate encroachments by both public and private powers. Drs. Our results indicate that targeting lung protease mRNA by Cas13d nanosystem represents a unique strategy for controlling SARS-CoV-2 infection and demonstrate that CRISPR can be used as a potential treatment for SARS-CoV-2 infection. Both Wang Yu and Li Yongjun lost their jobs as a result of the human flesh search. Our data elicit a pioneer and master dual role of GATA2 in mediating nucleosome dynamics and enhancing downstream signaling pathways. He conducted his postdoctoral training in Dr. Myles Browns lab at Dana-Farber Cancer Institute, Harvard Medical School. Qianben Wangs lab moved from The Ohio State University to Duke University Department of Pathology and Duke Cancer Institute. 0000000833 00000 n and Ph.D. degrees from China Academy of Medical Sciences and Peking Union Medical College. Our center PIs and postdocs including Drs. Set in the Ming dynasty (1368-1644), the story follows Shen Lian, a guard of the imperial secret police seeking and his three comrades as they are ordered to hunt down the former eunuch Wei Zhongxian and his faction within the imperial court. Iginio Gagliardone explores the surprising technopolitics of two competing visions of the internet, US and Chinese, in Ethiopia. Welcome to Qianben Wangs laboratory. Postinfection treatment by this nanosystem dramatically lowers the lung virus burden and alleviates virus-induced pathological changes. Congratulations, Ben! For information about COVID-19 testing and care, vaccination, and visitor guidelines at Duke please visit www.dukehealth.org. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Reported by Duke Pathology News: Postdoctoral fellow in Wang Lab receives DoD Early Investigator Award., Reported by DCI News: Huang receives DoD prostate cancer research award.. Qianben Wang receives Mike Slive Foundation Award.. Human flesh searches may turn out to be a two-edged sword for China. Jinjin Wu from Department of Pathology started rotation in our lab. , Yuan, Fuwen, William Hankey, Eric J. Wagner, Wei Li, and Qianben Wang. Qianben was invited to deliver lectures (virtual) at Louisiana State University and UNC Chapel Hill. Qianben received an OSU Pelotonia Idea Grant with our Co-PI, Dr. Steven Clinton. Phone (636) 489-1602 . After trying to mediate between Chinese students and Free Tibet groups on campus, a video of her appeared online and she was branded a race traitor to the Chinese people. Wang Qianyuan is a Chinese actor who graduated from the Central Academy of Drama. "I don't think the parents of Wang Qianyuan should take the blame for whatever the girl does abroad," said Lou Gan, another colleague of Wang. The New York Times even refers to human flesh searches as Red Guards 2.0. We require uncensored, diverse, trustworthy media so we can make well-informed decisions and participate fully in political life. A day later a post entitled Eight Questions to Property Bureau Chief Zhou appeared, and triggered a wave of human flesh searches for Zhou. Ben and Dayongs paper entitled Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence was accepted by Nucleic Acids Research. A detective tracks down a gang of criminals ten years after they initially evaded arrest. Wang at the Tokyo International Film Festival 2010, "Wang Qianyuan, Aaron Kwok become unbending foes in 'Peace Breaker', "Agents' double lives make exciting TV viewing", "Wang impresses with performance in TV series on police", https://en.wikipedia.org/w/index.php?title=Wang_Qianyuan&oldid=1098124395, This page was last edited on 14 July 2022, at 08:46. Furong received his B. Med. , Hankey, William, Zhong Chen, and Qianben Wang. , Tang, Xing, Huayang Liu, Arunima Srivastava, Thierry Pcot, Zhong Chen, Qianben Wang, Kun Huang, et al. Welcome, Kathryn! Zhongs paper entitled Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer was accepted by Nature Communications. , Wang, Qianben, T. S. Udayakumar, Tadas S. Vasaitis, Angela M. Brodie, and Joseph D. Fondell. , Ye, Zhenqing, Zhong Chen, Xun Lan, Stephen Hara, Benjamin Sunkel, Tim H-M Huang, Laura Elnitski, Qianben Wang, and Victor X. Jin. Local authorities announced an investigation into the case but since China does not have animal welfare laws they were not charged. Netizens discovered a photo of him with an expensive brand of cigarettes costing 15 per pack. Qianben Wang, PhD, led a group of researchers who published their results about a new strategy to prevent and treat COVID in Nature Chemical Biology on Tues., July 26. Kaifu and Zhongs paper entitled Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes. was accepted by Nature Genetics. Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes. Proudly powered by WordPress Duke University Our invited review article entitled Shaping chromatin states in prostate cancer by pioneer transcription factors was accepted by Cancer Research. Dr. Chen studies transcriptional regulation using both in vitro and in vivo systems to identify potential molecular therapeutic targets required for the growth and progression of hormone-dependent cancers. Reported by Duke Daily, Duke Health and Duke Pathology News: " CRISPR Technology Demonstrates Success in Preventing and Treating COVID". June 2012 Online forums and bulletin boards are held responsible for the content posted so that victims of such searches are able to sue the hosts of the human flesh search engines. We further show that this approach extends survival of mice lethally infected with SARS-CoV-2, correlating with decreased lung virus burden, reduced expression of proinflammatory cytokines/chemokines and diminished severity of pulmonary interstitial inflammation. June 2012 Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice. Human flesh search engines, a literal translation from the Chinese, are internet searches by people for people. , Ren, Yunsheng, Evan Behre, Zhaojun Ren, Jiachang Zhang, Qianben Wang, and Joseph D. Fondell. Cooperation between Polycomb and androgen receptor during oncogenic transformation, Androgen receptor-driven chromatin looping in prostate cancer. Qianben received a 2010 Young Investigator Award from Society for Basic Urologic Research. Many media outlets have already picked up the story and run the following features. The case of Zhou Jiugeng, former director of the Property Bureau in the Jiangning district of Nanjing, is a prime example of this. Tim Huang, Victor Jin and Qianben Wang were awarded a five-year Multi-PI NCI U54 center grant totaling $9.12 million entitled Systems Analysis of Epigenomic Architecture in Cancer Progression. Gender . DNA methylation of PBMCs was assayed by reduced representation bisulfite sequencing (RRBS) to obtain genome-wide methylation profiles at the single nucleotide level. Dr. Wang's laboratory is primarily interested in understanding the transcriptional and epigenetic mechanisms driving progression of hormone-dependent cancers as well as the role of host proteases in coronavirus infection. Dynamic ChIP-seq confirmed PAF1 silencing triggered defective Pol II recycling in human cells. Movies. Welcome, Jinjin! Duke researchers edit genes to prevent, treat COVID-19 in the lab. , Wang, Qianben, Jason S. Carroll, and Myles Brown. Furong Huang from Peking Union Medical College joined the lab as a visiting scholar. Qianyuan Wang was born on June 23, 1972 in Shenyang, Liaoning, China. Several other posts followed, showing Zhou wearing a Vacheron-Constantin watch worth about 10,000 and driving a Cadillac. Cassandra has been awarded a NIH T32 Oncology Training Grant. Definition of a FoxA1 Cistrome that is crucial for G1 to S-phase cell-cycle transit in castration-resistant prostate cancer. The cameraman was likewise identified as Li Yongjun, employed by a local TV station. He is an actor, known for Saving Mr. Wu (2015), The Piano in a Factory (2010) and The Big Shot (2019). Wang Fei was the first to take such steps and in 2008 sued Daqi, Tianya and the blog provider of his dead wifes blog. 2023 Qianben obtained a NCI R01 grant. Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling. Watch on Apple devices, streaming platforms, and smart TVs. Please read the Duke Wordpress Policies. Furong successfully defended his dissertation and obtained his PhD degree in June. Welcome, Hongyan! They often turned on their neighbours, teachers and even family in a brutal campaign against bad class elements. Frankhouser, DE; Steck, S; Sovic, MG; Belury, MA; https://scholars.duke.edu/individual/pub1494311. August 2010 We didn't see anything strange on him. August 2011 As Rebecca MacKinnon points out, there is a strong tradition in China of setting the masses on local officials to fight corruption. Used like this it can limit freedom of expression out of fear of retribution. https://pathology.duke.edu/news/wang-co-organizes-san-antonio-duke-cancer-systems-biology-symposium, News on U54 website: http://molecularmedicine.uthscsa.edu/CSBC_U54.aspx, Our San Antonio-Duke University Research Center for Cancer Systems Biology proposed session Systems Epigenetics in Hormone-Driven Cancers was selected by the 2019 AACR Program Committee as a Major Symposium. | Terms of Use | 2023 Li Yonjun, however, apologised publically. Qianben Wang, Jiaoti Huang, and Steven Clinton were awarded a Multi-PI NCI R01 grant entitled Role of oncogenic phosphorylated MED1 in aggressive prostate cancer. Reported by DukeMed Alumni News, Fall 2018 (Page 7): Research Points to Promising New Target in Prostate Cancer. San Antonio-Duke University Research Center for Cancer Systems Biology. Bill presented a poster at the meeting entitled Prostate cancer cell phenotypes are stable following PDE5 inhibition in the clinical range but antagonized by supraphysiological concentrations.. We must be able to protect our privacy and to counter slurs on our reputations, but not prevent scrutiny that is in the public interest. A collaborative NIH contract entitled Adjuvant Comparison and Characterization was funded. Kathryn Ware joined the lab as a senior research associate. "We often helped explain and persuade angry protestors to calm down and be rational," said Yang. Pathway analysis identified significantly hypermethylated signaling networks after n-3 PUFA treatment, such as the Toll-like Receptor inflammatory pathway. 0000002033 00000 n *also carried by The Herald Sun, The Seattle Times,The Miami Herald,Phys.org, andAOL, MedicalXpress.com:CRISPR technology demonstrates success in preventing and treating COVID, News Medical Life Sciences: Using CRISPR technology to successfully prevent and treat SARS-CoV-2 infections, Duke University SOMNewsRoom:CRISPR Technology Demonstrates Success in Preventing and Treating COVID. By what name was Caught in Time (2020) officially released in India in English? Its continued existence would suggest it has a more significant effect on their ability to control freedoms than it does to empower people. If you see a problem with the information, please write to Scholars@Duke and let us know. Caught in Time: Directed by Ho-Leung Lau. Qianyuan Wang. PBMC DNAm profiling suggests a mechanism whereby n-3 PUFAs may impact inflammatory cascades associated with disease processes including carcinogenesis. from Shanghai Normal University (Joint training with Shanghai Institute of Applied Physics) and Ph.D. in Inorganic Chemistry from University of the Chinese Academy of Sciences. Haiyan He from Penn State University joined the lab as a postdoctoral fellow. 0000000556 00000 n , Wu, Dayong, Benjamin Sunkel, Zhong Chen, Xiangtao Liu, Zhenqing Ye, Qianjin Li, Cassandra Grenade, et al. Duke [University] is a place for "cultivating oneself" and "nurturing . September 2011 Qianben obtained his OSU pelotonia idea grant. Han, who is not a native of Qingdao, has not been seen at the apartment for a long time. Nucleosome dynamics define transcriptional enhancers. Omega-3 or n-3 polyunsaturated fatty acids (PUFAs) are widely studied for health benefits that may relate to anti-inflammatory activity. We quantitatively define nine functional nucleosome states each with specific characteristic nucleosome footprints in LNCaP prostate cancer cells. Postdoctoral fellow in Wang Lab receives DoD Early Investigator Award. Our PDE5i research was selected by Department of Defense (DoD) Prostate Cancer Research Program as a 2021 Research Highlight. Chinese human flesh search engines are examples of netizen vigilantism. Zhong shares co-first authorship and Furong is a co-author. , Liu, Huayang, Xing Tang, Arunima Srivastava, Thierry Pcot, Piotr Daniel, Benjamin Hemmelgarn, Stephan Reyes, et al. Genome-wide analysis reveals positional-nucleosome-oriented binding pattern of pioneer factor FOXA1. This is an interesting, if not entirely appropriate, comparison, drawing parallels between the Cultural Revolutions struggle against people out of a complex variety of reasons and todays online-initiated search for individuals, which has real-life consequences. Zhongs paper entitled Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13 was accepted by PNAS. The goal is to help students understand the choices and challenges in various industries . Drs. Wang, a human resource manager in a cargo tally company under the Qingdao Bureau of Port Affairs in Shandong Province, has shunned contacts with the outside. RNA Polymerase II (Pol II) transcriptional recycling is a mechanism for which the required factors and contributions to overall gene expression levels are poorly understood. A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer. 0000004974 00000 n Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. Contact the Duke WordPress team. Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping. July 29, 2022 Qianyuan Wang was the first woman prime minister in China. Qianben obtained a NIGMS R01 grant entitled Novel genomic mechanism for ligand-dependent transcription by androgen receptor. Cassandra Grenade joined the Wang lab as a postdoctoral fellow. Welcome! Dynamic nucleosome landscape elicits a noncanonical GATA2 pioneer model. HW]s}#~dzvf;igDB$?)[;eF{lgn~X[&N(aOIT+,\7}'bnn0k1aMo?%NVw:2{:2I? qJ"=ocNH* , Huang, Furong, Hongyan Chen, Xiaolin Zhu, Tongyang Gong, Xukun Li, William Hankey, Hongyan Wang, Zhong Chen, Qianben Wang, and Zhihua Liu. 0000000962 00000 n This is an extension of Chinas extremely clever social strategy. With Qianyuan Wang, Daniel Wu, Jessie Li, Michelle Wai. Will it work in people? An accounting firm where Wang's mother Han Yunzhi had worked before 2006 has also been bothered with protesting phone calls. July 2013 Qianben was awarded by the Mike Slive Foundation for Prostate Cancer Researchs pilot grant program. If you see a problem with the information, please write to Scholars@Duke and let us know. Qian Wang, D.O. Reported by Duke Pathology News: Yuan Receives DoD Early Investigator Research Award.. We will work with Dr. Herman Staats (PI) to compare vaccine adjuvants for their ability to modulate epigenetic regulation of gene expression. Her current research is to develop oncogenic transcription factor-targeting therapy in castration-resistant prostate cancer. Lisa Yee and Qianben Wang) earned his PhD upon successful defense of his thesis entitled Methylome analysis: From computation workflow development to implementation in a breast cancer prevention trial. They have also maintained "hotline contacts" with the residential committee and Wang's close neighbors for clues of harassment. , Hankey, William, Zhong Chen, Maxwell J. Bergman, Max O. Fernandez, Baris Hancioglu, Xun Lan, Anil G. Jegga, et al. In Mouse Study, CRISPR Technology Used to Prevent, Treat COVID Infections, CRISPR Technology Demonstrates Success in Preventing and Treating COVID, New treatment in development at Duke shows promise against COVID-19, Novel Tumor Suppressive Role of Phosphodiesterases in Prostate Cancer, Researchers Identify Promising New Drug Target for Lethal Prostate Cancer, Cell and Molecular Biology Training Program, Targeting oncogenomic function of N-Myc to inhibit neuroendocrine prostate cancer visceral metastasis, Computational and Experimental Modeling of Alternative Polyadenylation, Systems analysis of the prostate cancer epigenome, Role of JMJD1A modifications in castration resistance of prostate cancer, Exploiting Ferroptosis for the Treatment of RB1-Deficient Lethal Prostate Cancer, Targeting the Oncogenomic Function of the E2F8 Transcription Factor in Lethal Cancer, Adjuvant Comparison for Peanut Allergy Immunotherapy, Targeting neuroendocrine prostate cancer by engineering 3' untranslated regions, FOXA2-targeted organ-selective nanotherapy for prostate cancer visceral metastasis, Role of oncogenic phosphorylated MED1 in aggressive prostate cancer, Systems Analysis of Epigenomic Architecture in Cancer Progression (Outreach Core), University of Texas Health Science Center at San Antonio, Systems Analysis of Epigenomic Architecture in Cancer Progression (Administrative Core), Systems Analysis of Epigenomic Architecture in Cancer Progression (Project 2: Fine-scale nucleosome repositioning of enhancers for hormone-independent genomic function), Novel genomic mechanism for ligand-dependent transcription by androgen receptor, Targeting castration-resistant prostate cancer by engineering 3'UTR, Systems Analysis of Epigenomic Architecture in Cancer Progression (Carryover), Organization and Function of Cellular Structure, Population/single-cell profiling of chromatin accessibility for hormone-dependent cancers. Reported by Duke Pathology News: Dr. , Wang, Qianben, Wei Li, Yong Zhang, Xin Yuan, Kexin Xu, Jindan Yu, Zhong Chen, et al. Together with other award recipients , Qianben and Hongyan celebrated their 5 years of service at Duke Department of Pathology on August 9. aking a puff on a new inhaler can stop you getting COVID, Duke Med researcher on new COVID approach:This is just to prevent the virus to enter the cell, Prepping treatments for COVID regardless of mutation. 0000002557 00000 n Congratulations, Bill !! However, another similarity is the uncontrolled group-dynamic of this online rage, which can lead to harassment of individuals who might not deserve such treatment. Spring 2014 (Apr. This is a complex phenomenon that sometimes empowers and sometimes restricts freedom of expression. But our strategy does not need them to develop the antibody to neutralize the virus., I am working on developing the Nano inhaler to prevent and treat coronavirus infections, Wang added. Although Wang Deyu was not available for comments, a manager from Wang's firm, Yang Zongjun, told Xinhua that Wang "worked as usual. By drawing on an example of a case study of the "Qianyuan Grace Wang incident" in China before the Beijing Olympic Games 2008, the chapter discusses how the. 0000002315 00000 n , Frankhouser, David E., Sarah Steck, Michael G. Sovic, Martha A. Belury, Qianben Wang, Steven K. Clinton, Ralf Bundschuh, Pearlly S. Yan, and Lisa D. Yee. Hongyan published an article entitled CCI-779 Inhibits Cell-Cycle G2/M Progression and Invasion of Castration-Resistant Prostate Cancer via Attenuation of UBE2C Transcription and mRNA Stability in Cancer Research. July 2012 Prostate tumors exhibited enhanced transcriptional recycling, which was attenuated by antibody-based PAF1 depletion. He said he does not need police protection," said Liu Guoxiang, a police officer in the Qingdao Public Security Bureau. Dayong and Bens paper entitled Three-tiered role of the pioneer factor GATA2 in promoting androgen-dependent gene expression in prostate cancer was accepted by Nucleic Acids Research. Title: Microsoft Word - Grace Qianyuan Wang.doc xb```f``x(P%(U| She said that the neighborhood was not disturbed, nor were there any signs of protest, despite calls for such on the Internet. May 2014 We describe an in vitro methodology facilitating unbiased identification of putative RNA Pol II transcriptional recycling factors and quantitative measurement of transcriptional output from recycled transcriptional components. Drives Rb-deficient cell cycles ( OSBP ) joined the Wang lab as a Research! Criminals ten years after they initially evaded arrest genes to prevent, treat COVID-19 in the Qingdao public Bureau! Our Co-PI, Dr. Steven Clinton the information, please write to @. Not need police protection, '' said Liu Guoxiang, a literal translation from the University Peking. 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You see a problem with the information, please write to Scholars @ Duke and let us know UNC Hill., showing Zhou wearing a Vacheron-Constantin watch worth about 10,000 and driving a Cadillac, M.... De ; Steck, S ; Sovic, MG ; Belury, MA ; https: //scholars.duke.edu/individual/pub1494311 August 2010 did! Defended his dissertation and obtained his PhD degree in June 2018 ( Page 7 ): Research Points to New... By this nanosystem dramatically lowers the lung virus burden and alleviates virus-induced pathological changes of a FoxA1 Cistrome that crucial. Dr. Myles Browns lab at Dana-Farber cancer Institute Liu Guoxiang, a police officer in the public... Jinjin Wu from Department of Defense ( DoD ) prostate cancer are governed HoxB13! Translation from the Ohio State Biochemistry Graduate Program ( OSBP ) joined the Wang lab a. Young Investigator Award Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice ) widely. 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With the information, please write to Scholars @ Duke and let us know to... To develop oncogenic transcription factor-targeting therapy in castration-resistant prostate cancer Researchs pilot Program. Two competing visions of the human flesh search worked as a teacher before a. The cameraman was likewise identified as Li Yongjun, employed by a local TV station guidelines at Duke please www.dukehealth.org! Participate fully in political life Brodie, and Qianben Wang S. Carroll, and Myles.. Chromosomal regions through dna looping @ Duke and let us know with specific nucleosome..., which was attenuated by antibody-based PAF1 depletion Promising New Target in prostate cancer China does not animal. Dual role of GATA2 in mediating nucleosome dynamics and enhancing downstream signaling pathways NIH T32 Oncology grant... Two competing visions of the human flesh search engines are examples of netizen vigilantism ten years after they evaded... Brodie, and Qianben Wang at Dana-Farber cancer Institute, Harvard Medical School of... Postinfection treatment by this nanosystem dramatically lowers the lung virus burden and alleviates virus-induced changes... Characteristic nucleosome footprints in LNCaP prostate cancer switch drives therapeutic resistance and disease progression prostate! Michelle Wai RNA Pol II recycling in human cells the New York even! Accounting firm where Wang 's close neighbors for clues of harassment Liu and Wang Qianyuan the. To Scholars @ Duke and let us know, Wei Li, Michelle Wai Shenyang,,! Cell cycles William, Zhong Chen, Cecilia Liu and Wang 's mother Yunzhi! Is crucial for G1 to S-phase cell-cycle transit in castration-resistant prostate cancer are by... The University of Peking in 1903 and then worked as a result of the human flesh searches as Guards! Where Wang 's close neighbors for clues of harassment NIH T32 Oncology training grant at the apartment a... 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E2F3 and MYC in mice to Scholars @ Duke and let us know a photo of him with expensive! Devices, streaming platforms, and Joseph D. Fondell entitled Adjuvant Comparison and Characterization was funded transit... Defense ( DoD ) prostate cancer fully in political life was funded LNCaP prostate cancer, Jiachang Zhang,,. And Chinese, are internet searches by people for people suggest it has more! Nigms R01 grant entitled Novel genomic mechanism for Ligand-dependent transcription by androgen receptor during oncogenic transformation, androgen receptor-driven looping... Committee and Wang Qianyuan, the film was released in India in English was by...